17 Hydroxyprogesterone Blood Test
17 Hydroxyprogesterone Test (Labcorp)
This test measures the level of 17 hydroxyprogesterone in a blood sample. 17-hydroxyprogesterone (17-OH Progesterone) is a hormone that is produced by the adrenal glands as part of the process of producing cortisol. Cortisol plays an important role in regulating metabolism and maintaining a healthy immune system. In people with the inherited disorder Congenital Adrenal Hyperplasia (CAH), their bodies are unable to produce one or more of the enzymes necessary for cortisol production. This causes a buildup in 17-oh progesterone as the body is unable to convert it into cortisol. CAH also typically causes elevated levels of androgen, male sex hormones such as testosterone, which are also produced by the adrenal glands but do not require the missing enzymes used in cortisol production.
CAH is more common in infants or children but can develop in adults as well. Common symptoms of CAH in women include irregular menstrual periods, a deep voice, excessive hair growth, and infertility. CAH can also cause infertility in men. Measuring the level 17-hydroxyprogesterone in the blood is one of the ways a person's doctor can diagnose CAH. 17-hydroxyprogesterone testing can also help to monitor someone who is being treated for CAH.
This test is typically ordered when someone has symptoms of Congenital Adrenal Hyperplasia or is being treated for this disorder. It may be ordered along with other blood tests such as Cortisol and Adrenocorticotropic Hormone (ACTH).
Turnaround for this test is typically 3-8 business days.
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