Adrenal 21 Hydroxylase Autoantibodies Blood Test
Test Code: 504805
Specimen Type: Blood
Adrenal 21 Hydroxylase Autoantibodies Blood Test (Labcorp)
This test measures a type of autoantibody that is often present in people with adrenal insufficiency. The adrenal glands are located on top of the kidneys and produce several important hormones including cortisol and aldosterone. Adrenal insufficiency is a condition in which the adrenal glands do not produce enough of these vital hormones. The most common cause of adrenal insufficiency is an autoimmune disorder in which the body's own immune system mistakenly attacks the cells and tissues of the adrenal gland. The most prevalent of these disorders are Addison's Disease and Autoimmune Adrenalitis. Approximately 86% of people with autoimmune adrenal insufficiency show elevated levels of antibodies to 21-Hydroxylase, a hormone found in the membranes of the adrenal gland. Testing for 21-hydroxylase autoantibodies can help to identify Addison's disease or other disorders as well as differentiate them from other conditions with similar symptoms.
Blood testing for 21-hydroxylase antibodies is typically ordered when a person is experiencing symptoms of adrenal insufficiency. These symptoms can include fatigue, weight loss, darkening of the skin, low blood pressure, fainting, abdominal pain, nausea, vomiting, muscle or joint pain, depression, irritability, and unexplained hair loss.
Turnaround for this test is typically 4-15 business days.
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