Immunoglobulin G (IgG), Subclasses Blood Panel
Test Code: 209601
Specimen Type: Blood
Immunoglobulin G (IgG), Subclasses Blood Panel (Labcorp)
This test measures the total level of Immunoglobulin G (IgG) as well as the 4 main subclasses of IgG in a blood sample. Immunoglobulins are antibodies produced by the body's immune system to target and eliminate foreign objects such as viruses and bacteria. Immunoglobulin G is the most abundant type of antibody in the blood. There are 4 subclasses of IgG which are known as IgG1, IgG2, IgG3, and IgG4. Normmaly IgG1 makes up about 65% of total IgG with IgG2 making up about 25%. IgG3 usually makes up about 6% and IgG4 makes up about 4%. Each subclass of IgG has different properties that allow them to combat different types of infections.
Measuring IgG subclasses is typically done to help determine if someone has deficiencies in one or more types of IgG. These types of immunodeficiencies can make people more susceptible to certain types of diseases or infections. An IgG subclass test can provide more information than a regular Total IgG blood test. People with deficiencies in one or more IgG subclasses may suffer from chronic infections or have difficulty fighting off certain infections even when their total IgG levels appear normal.
An IgG subclasses test is typically performed as a follow-up to a Total IgG test. It is often ordered along with other tests including Immunoglobulin A and Immunoglobulin M to help assess the state of a person's immune system.
Turnaround for this test is typically 3-7 business days.
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