The Thyroglobulin Panel measures levels of both Thyroglobulin and Thyroglobulin Antibodies in the blood. Thyroglobulin is a protein produced by the Thyroid Gland which is used in the production of the thyroid hormones T3 and T4. Normally, levels of thyroglobulin are very low. Certain conditions such as Graves Disease, Hashimoto Thyroiditis and several types of Thyroid Cancer can cause Thyroglobulin levels to become elevated. Measuring Thyroglobulin can help aid in the diagnosis of these conditions as well as monitor treatment. However, people with autoimmune disorders may have Thyroglobulin Antibodies in their body which can interfere with a Thyroglobulin Test. For this reason, a Thyroglobulin Antibody test is performed first to determine which methodology will be most effective for testing Thyroglobulin. If the Thyroglobulin Antibody test is negative, Thyroglobulin will be measured using the immunometric assay (IMA) methodology. If the Thyroglobulin Antibody is positive, Thyroglobulin will be measured with LC/MS-MS methodology.
This test is typically ordered when a person has irregular results from other thyroid tests such as TSH, T3 or T4. It may also be ordered prior to surgery for Thyroid Cancer or to monitor treatment for several conditions.
Turnaround for this test is typically 4-8 business days.
Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.
The Thyroglobulin Panel may exhibit interference when a sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to stop biotin consumption at least 72 hours prior to the collection of a sample.