Diphenhydramine (Benadryl) Urine Drug Test
Specimen Type: Urine
Diphenhydramine (Benadryl) Urine Drug Test (Labcorp)
This test looks for Diphenhydramine, more commonly known by the brand name Benadryl, in the urine. Diphenhydramine is an antihistamine that is used in medications that help to manage the symptoms of allergies, hay fever, and the common cold. During an allergic reaction, the body produces histamine which causes symptoms such as itching, rash, watery eyes, runny nose, sneezing, and irritation in the throat and nose. Benadryl temporarily blocks histamine production to relieve these symptoms. Diphenhydramine is also sometimes used to treat motion sickness, insomnia, and early-stage Parkinson's disease. Benadryl and Diphenhydramine are sometimes taken recreationally to produce a high or enhance the effects of other drugs including alcohol.
Benadryl and other diphenhydramine products are some of the most abused over the counter medications in the US due to how easy it is to obtain them. Overusing these products or taking them in conjunction with other drugs or alcohol can cause a variety of side effects. These include dizziness, blurred vision, increased heart rate, nausea, weakness, anxiety, memory loss, confusion, nightmares, and depression. In severe cases, overdosing can lead to hallucinations, seizures, liver or kidney damage, respiratory failure, or heart attack.
Diphenhydramine is not included in most standard drug tests so a specific test is needed when someone is suspected of abusing or overusing it. The detection period for diphenhydramine in urine will vary depending on a number of factors but in most cases, it will be detectable for 2-4 days after use. The detection period may be longer in cases of continued use or high dosage. Positive results for this test will give a numerical value for the level detected.
A blood test for Diphenhydramine (Benadryl) is also available. For more testing options, please see our Drug Testing Category.
Turnaround for this test is typically 10-14 business days.
Where can I find a Diphenhydramine (Benadryl) drug test near me?
Check our lab finder to locate a collection site in your area.
At this time, Request A Test does not offer DOT (Department of Transportation) certified testing.
Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.
Please be aware that due to national staffing shortages at the labs, results for drug testing may take longer than normal. Request A Test cannot guarantee turnaround time for test results.
Please note that not all lab locations are able to perform the collections for blood drug testing. When placing a testing order online you will only be able to select from lab locations that are able to perform this type of testing.
This test is intended to screen for drugs of abuse and is not appropriate for pain management or therapeutic monitoring. Customers who require pain management testing should consult their prescribing physician.