Human Epididymis Protein 4 (HE4) test
Human Epididymis Protein 4 (HE4) Test
This test measures levels of Human Epididymis Protein 4 (HE4) in the blood. HE4 is a protein that is produced by Epithelial Ovarian Cancer Cells. Epithelial Ovarian Cancer is the most common type of Ovarian Cancer accounting for about 90% of cases. Many, but not all, women with ovarian cancer will show elevated levels of HE4. HE4 is most useful as a tumor marker and can be used in some cases to monitor how well a person is responding to treatment. The HE4 test is not recommended as a screening for cancer since other healthy types of cells also produce HE4 and the presence of HE4 is not a clear indicator that a person has ovarian cancer.
An HE4 test is typically ordered after a person has been diagnosed with ovarian cancer to establish a baseline level. Subsequent testing can then be used to monitor disease progression and response to treatment. HE4 is often ordered along with a CA 125 test.
Turnaround for this test is typically 2-4 business days.
Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.
It is recommended that someone taking Biotin (also known as vitamin B7 or B8, vitamin H, or coenzyme R) stop consumption at least 72 hours prior to the collection of a sample.