Liver Kidney Microsome (LKM) Antibody Blood Test
Liver Kidney Microsome (LKM) Antibody Test (Labcorp)
This test measures the level of Liver-Kidney Microsome (LKM) Type 1 Antibodies in a blood sample. LKM antibodies are a type of autoantibody that targets a protein found primarily in the liver. The presence of LKM antibodies is typically associated with Type 2 Autoimmune Hepatitis. Hepatitis is a series of conditions that cause inflammation of the liver and can lead to cirrhosis and liver failure. Autoimmune Hepatitis is a disorder in which the body's own immune system mistakenly targets cells in the liver. There are 2 primary types of Autoimmune Hepatitis. Type 1 is more common and often affects people with other types of autoimmune disorders such as Sjogren's Syndrome, Type 1 Diabetes, and Ulcerative Colitis. Type 2 is less common but tends to be more severe. When someone has common symptoms of liver disease including jaundice, fatigue, and weakness, blood tests including LKM antibodies can help identify the cause.
An LKM Antibody test is typically ordered to help find the cause of liver damage. LKM is often ordered with other tests including an Actin Smooth Muscle Antibody (ASMA) and Antinuclear Antibody (ANA) to help diagnose and differentiate between the 2 forms of Autoimmune Hepatitis. These tests may be done as a followup to irregular results on a Hepatic Function Panel.
Turnaround for this test is typically 2-4 business days.
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