Scleroderma (Scl-70) Blood Test
Test Code: 018705
Specimen Type: Blood
Scleroderma (Scl-70) Blood Test (Labcorp)
This test looks for Anticleroderma-70 Antibodies (Anti-Scl 70) in the blood. The presence of Anti-Scl 70 antibodies is typically associated with Scleroderma, a connective tissue disease that affects the skin and other tissues including blood vessels, organs, and the digestive tract. Research into the causes of scleroderma is ongoing. It is typically considered to be an autoimmune disorder and people with Scleroderma often have other disorders such as rheumatoid arthritis or Sjogren's syndrome. Other factors such as genetics, family history, chronic illness, or exposure to certain harmful chemicals have also been linked to the development of scleroderma. Scleroderma can affect different people in different ways. Common symptoms include developing patches of hardened tightened skin, fingers or toes that turn blue and numb in cold temperatures, heartburn, bloating, cramping, constipation, and diarrhea. Long-term health complications can include chronic digestive issues, loss of lung capacity, high blood pressure, heart failure, kidney disease, sexual dysfunction, and loss of blood flow to fingers or toes which may necessitate amputation.
Not everyone with Scleroderma will show positive results on an Anti-Scl 70 test and a negative result does not rule out the possibility of having the disease. Additional testing and evaluation by your doctor are necessary for a diagnosis. Other tests including an Antinuclear Antibody (ANA) test can help provide more information
This test is often ordered when a person has symptoms of connective tissue disease. It is sometimes done along with or as a follow-up to an Antinuclear Antibody test.
Turnaround for this test is typically 2-4 business days.
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