Centromere B Antibody Blood Test
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Test Code: 164814
Specimen Type: Blood
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Description:
Centromere B Antibody Blood Test (Labcorp)
This test measures the level of anticentromere B antibodies in a blood sample. Centromere B antibodies are a type of antinuclear antibody which are typically found in people with CREST syndrome. CREST syndrome is a form of scleroderma, a connective tissue disease. CREST is named for the primary symptoms that it causes.
- Calcinosis – Calcium deposits forming under the skin
- Raynaud phenomenon – Decreased circulation in the fingers and toes, causing them to turn white and blue
- Esophageal dysfunction – Difficulty swallowing, acid reflux, and heartburn
- Sclerodactyly – Tight, thick, shiny skin developing on the hands and fingers
- Telangiectasia – Red spots that appear on the skin due to swollen capillaries
As much as 95% of people with CREST syndrome will test positive for centromere B antibodies. People with other forms of scleroderma as well as conditions such as cirrhosis, rheumatoid arthritis, and lupus have also been shown to produce centromere B antibodies. Centromere B antibody testing can aid in diagnosing CREST syndrome as well as differentiating it from other autoimmune disorders with similar symptoms.
This test may be ordered as a follow-up to a positive result on an antinuclear antibody (ANA) test, especially if someone has one or more symptoms of CREST syndrome.
Turnaround for this test is typically 2-4 business days.
Where can I find a Centromere B Antibody test near me?
Check our lab finder to locate a collection site in your area.
Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.
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