AChR Binding Antibody Serum Test

Sample Report Test Code: 085902 Specimen Type: Blood

Description:

AChR (Acetylcholine Receptor) Binding Antibody Serum Test (Labcorp)

This test measures Acetylcholine Receptor (ACHR) Binding Antibodies levels in serum (blood).  ACHR antibodies are a type of autoantibody produced by the immune system which mistakenly targets proteins in the muscles.  These proteins, called acetylcholine receptors, allow communication between nerve and muscle fibers.  Damage to these proteins caused by ACHR antibodies can cause muscle fatigue.  ACHR antibodies are associated with the autoimmune disorder Myasthenia Gravis (MG).  People with myasthenia gravis typically experience symptoms such as drooping eyelids, slurred speech, difficulty holding up their head, difficulty breathing, difficulty walking, and weakness in muscles throughout the body. 

There are 3 types of ACHR antibodies that each affect the receptor proteins differently.  Binding antibodies are the most common, being found in 85-90% of people with MG.  They attach to nerve cells and cause an inflammatory response which damages or destroys the receptors.  The other 2 types are Blocking and Modulating antibodies.   

Testing for ACHR binding antibodies may be ordered when a person is experiencing common symptoms of myasthenia gravis.  Results can help to diagnose MG or differentiate it from other conditions with similar symptoms.  A Myasthenia Gravis Panel which looks at all 3 types of AChR antibodies is also available. 

Turnaround for the AChr Binding Ab Serum Test is typically 3-5 business days.

Where can I find a AChR (Acetylcholine Receptor) Binding Antibody test near me?

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