Comprehensive Hepatitis B Profile Test

Hep B Surface Ag, Surface Ab, Core Ab IgM, Core Ab Total, Be Ag, Be Ab


Test Code: 058545
Specimen Type: Blood

Description:

Comprehensive Hepatitis B Profile Test

This panel includes 6 tests that can aid in diagnosing infection with Hepatitis B.  Hepatitis B is a viral liver infection that is spread through exposure to infected blood or bodily fluids.  It is the most common cause of acute viral Hepatitis.  Hep B is spread through contact with infected blood or bodily fluids.  The most common means of transmission are through sexual contact or sharing needles used for intravenous drug use.  Infected mothers can also pass the virus to their infants during childbirth.  Hepatitis B infections often show no symptoms but when symptoms do occur they can include abdominal pain, fever, loss of appetite, nausea, joint pain, fatigue, jaundice, and dark-colored urine.  Chronic Hep B infections can cause serious health complications like Cirrhosis and Liver Cancer.  Vaccination against Hep B is available which can provide immunity to the virus.  People who are successfully treated for Hep B typically develop a natural immunity that can protect against future infections.

This panel combines 6 tests that can provide more information when used together than any single test.  Used in combination, these tests can help to determine if a person has been exposed to Hep B and whether they have an active infection.  These tests can also be useful for determining if a person has immunity to the Hep B Virus.  Results for these tests may have more than one interpretation and should be reviewed by a person's doctor.

This panel includes:

  • Hep B Surface Antigen: A protein on the surface of the Hep B Virus.  Positive results indicate a current infection which can be either acute or chronic.
  • Hep B Surface Antibody (Qualitative): Antibodies that provide protection from future infection.  Positive results typically indicate immunity due to vaccination or recovery from a previous infection.  Results are positive or negative (not numerical.)
  • Hep B Core Antibody, IgM: Antibodies that develop shortly after infection and fade out over time.  Positive results typically indicate a recent or acute infection.
  • Hep B Core Antibody, Total: Antibodies that develop during infection and persist for life.  Results from this test can be used in conjunction with other tests to help determine if an infection is acute or chronic as well as determine the source of immunity.
  • Hep Be Antigen: A protein that is produced when the Hep B virus is actively replicating.  Positive results typically indicate an active infection.
  • Hep Be Antibody: An antibody that is produced after the successful treatment of the virus.  Positive results typically indicate successful treatment or latent infection.

A less comprehensive Hepatitis B Panel which includes 3 tests is also available.  For other testing options please see our Hepatitis Testing Category.

Turnaround for this test is typically 2-6 business days.

Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Incubation Period:

An active Hepatitis B infection is typically detectable 4-12 weeks after infection or any time after.  Some people may be detectable earlier.

The surface antibody to Hep B is typically detectable 1-2 months after vaccination.

Requirements:

It is recommended that someone taking Biotin (also known as vitamin B7 or B8, vitamin H, or coenzyme R) stop consumption at least 72 hours prior to the collection of a sample.

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Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Categories:


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