Scleroderma Blood Test

Scleroderma Blood Test

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Scleroderma Blood Test

What is Scleroderma?

Scleroderma is an autoimmune disorder that causes an overproduction of collagen.  Collagen is a protein that makes up connective tissues in the body such as the skin and muscles.  Scleroderma causes tissues to become hard and fibrous impairing their ability to function properly.  The severity of the disease can vary from person to person and it can cause a range of issues from mild cosmetic symptoms to serious organ failure.  There are generally 2 categories that scleroderma cases fall into, Localized and Systemic.  Localized scleroderma is relatively mild, affects only a few areas of the skin and muscles, and rarely spreads to the organs.  Systemic scleroderma (systemic sclerosis) can affect many parts of the body including the gastrointestinal tract, lungs, kidneys, heart, and other organs.

What are the symptoms of Scleroderma?

Scleroderma symptoms can range from mild to severe depending on a person's conditioning and what part(s) of the body are affected.  The most common sign of scleroderma is the development of thick hardened patches of skin.  Other common symptoms include joint pain, swelling in the hands or feet, loss of circulation in the fingers or toes, fatigue, weakness, difficulty swallowing, dry mouth, lack of appetite, unexplained weight loss, constipation, and diarrhea.  Many of these symptoms are common to other disorders which can make scleroderma difficult to identify.  Scleroderma blood tests can help a person's doctor to diagnose scleroderma and differentiate it from other similar conditions.

What is a Scleroderma Blood Test?

Identifying scleroderma early and determining an effective treatment can help prevent serious health complications.  There is no single test that can diagnose or rule out scleroderma.  Typically, people who display symptoms of scleroderma will need to take a number of tests.  The results of these tests can be interpreted along with a person's clinical symptoms to determine if they suffer from scleroderma.  There are several common scleroderma blood tests.

  • Antinuclear Antibodies (ANA): About 95% of people with scleroderma will test positive for ANA antibodies.  The pattern their test results display can help differentiate scleroderma from other types of autoimmune disorders.
  • SCL-70 Antibodies: About 60% of cases of systemic sclerosis will test positive for SCL-70 antibodies.
  • Centromere-B: Centromere antibodies are present in a majority of people with a form of scleroderma known as CREST syndrome.

How do I get a Scleroderma Blood Test?    

Request A Test gives you the power to take charge of your own health and order affordable lab testing whenever you need it.  We offer a full menu of testing options including Autoimmune Disorder testing which can be used to aid in identifying scleroderma cases.  Placing an order is easy and does not require insurance or a doctor's visit.  Order online anytime at or call us at 1-888-732-2348 to speak to a representative who can help place your order or answer any questions you may have.  Placing an order is quick and easy and once your order is set up you can go to the lab that same day or whenever it is convenient.  Contact us today to get started.

Why Choose Us?

  • Since 2002, we have a proven track record of offering excellent customer service, affordable pricing with no hidden fees, and our enduring commitment to protect your personal information.
  • No doctor's order? (No problem!) Our national physician network provides the required doctor's order for the lab. Insurance is not needed to order lab testing nor will your insurance company be billed.
  • We are partnered with two of the largest CLIA-certified labs in the US, to offer you the latest lab testing technology with prompt and accurate results. (These are the same labs used by hospitals and physicians.)
  • With over 3,600 lab locations to choose from and same-day collection, we make lab testing quick and convenient. No appointment is needed. Find your local lab with our location finder.
  • We offer an extensive and detailed test menu. Ordering can be done online or over the phone. Not finding a test? Simply give us a call.  

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